All-trans-retinoic acid induces RARB-dependent apoptosis via ROS induction and enhances cisplatin sensitivity by NRF2 downregulation in cholangiocarcinoma cells

All-trans-retinoic acid (ATRA) has been clinically used to treat acute promyelocytic leukemia and is being studied to treat other types of cancer; however, the therapeutic role and mechanism of ATRA against cholangiocarcinoma (CCA) remain unclear. The present study investigated the cytotoxic effect...

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Detalles Bibliográficos
Autores principales: Butsri, Siriwoot, Kukongviriyapan, Veerapol, Senggunprai, Laddawan, Kongpetch, Sarinya, Prawan, Auemduan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025595/
https://www.ncbi.nlm.nih.gov/pubmed/35464301
http://dx.doi.org/10.3892/ol.2022.13299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025595/
https://www.ncbi.nlm.nih.gov/pubmed/35464301
http://dx.doi.org/10.3892/ol.2022.13299

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