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All-trans-retinoic acid induces RARB-dependent apoptosis via ROS induction and enhances cisplatin sensitivity by NRF2 downregulation in cholangiocarcinoma cells
All-trans-retinoic acid (ATRA) has been clinically used to treat acute promyelocytic leukemia and is being studied to treat other types of cancer; however, the therapeutic role and mechanism of ATRA against cholangiocarcinoma (CCA) remain unclear. The present study investigated the cytotoxic effect...
Autores principales: | Butsri, Siriwoot, Kukongviriyapan, Veerapol, Senggunprai, Laddawan, Kongpetch, Sarinya, Prawan, Auemduan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025595/ https://www.ncbi.nlm.nih.gov/pubmed/35464301 http://dx.doi.org/10.3892/ol.2022.13299 |
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