Polymerized β-Cyclodextrin-Based Injectable Hydrogel for Sustained Release of 5-Fluorouracil/Methotrexate Mixture in Breast Cancer Management: In Vitro and In Vivo Analytical Validations

An inclusion complexation, between polymerized β-cyclodextrin and cholesterol end-capping branched polyethylene glycol, was utilized for constructing a self-assembled hydrogel. The physicochemical properties, the in vitro release profiles of 5-Fluorouracil/methotrexate (anticancer drugs), and the su...

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Detalles Bibliográficos
Autores principales: Almawash, Saud, El Hamd, Mohamed A., Osman, Shaaban K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025605/
https://www.ncbi.nlm.nih.gov/pubmed/35456651
http://dx.doi.org/10.3390/pharmaceutics14040817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025605/
https://www.ncbi.nlm.nih.gov/pubmed/35456651
http://dx.doi.org/10.3390/pharmaceutics14040817

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