Anti-β2-GPI Antibodies Induce Endothelial Cell Expression of Tissue Factor by LRP6 Signal Transduction Pathway Involving Lipid Rafts

In this study we analyzed whether anti-β2-GPI antibodies from patients with APS induce the endothelial cell expression of Tissue Factor (TF) by a LRP6 signal transduction pathway involving lipid rafts. HUVEC were stimulated with affinity purified anti-β2-GPI antibodies. Both LRP6 and β-catenin phosp...

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Detalles Bibliográficos
Autores principales: Riitano, Gloria, Capozzi, Antonella, Recalchi, Serena, Caissutti, Daniela, Longo, Agostina, Mattei, Vincenzo, Conti, Fabrizio, Misasi, Roberta, Garofalo, Tina, Sorice, Maurizio, Manganelli, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025633/
https://www.ncbi.nlm.nih.gov/pubmed/35455968
http://dx.doi.org/10.3390/cells11081288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025633/
https://www.ncbi.nlm.nih.gov/pubmed/35455968
http://dx.doi.org/10.3390/cells11081288

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