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Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway

Muscle atrophy in postmenopausal women is caused by estrogen deficiency and a variety of inflammatory factors, including tumor necrosis factor alpha (TNFα). Paeoniflorin (PNF), a natural compound with anti-inflammatory properties, improves estradiol synthesis. Here, we demonstrate that PNF inhibits...

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Detalles Bibliográficos
Autores principales: Park, Ki-Sun, Kim, Hyungjun, Kim, Hye Jin, Lee, Kang-In, Lee, Seo-Young, Kim, Jieun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025649/
https://www.ncbi.nlm.nih.gov/pubmed/35455387
http://dx.doi.org/10.3390/ph15040390