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IntroSpect: Motif-Guided Immunopeptidome Database Building Tool to Improve the Sensitivity of HLA I Binding Peptide Identification by Mass Spectrometry

Although database search tools originally developed for shotgun proteome have been widely used in immunopeptidomic mass spectrometry identifications, they have been reported to achieve undesirably low sensitivities or high false positive rates as a result of the hugely inflated search space caused b...

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Detalles Bibliográficos
Autores principales: Zhang, Le, Liu, Geng, Hou, Guixue, Xiang, Haitao, Zhang, Xi, Huang, Ying, Zhang, Xiuqing, Li, Bo, Lee, Leo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025654/
https://www.ncbi.nlm.nih.gov/pubmed/35454168
http://dx.doi.org/10.3390/biom12040579