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IntroSpect: Motif-Guided Immunopeptidome Database Building Tool to Improve the Sensitivity of HLA I Binding Peptide Identification by Mass Spectrometry
Although database search tools originally developed for shotgun proteome have been widely used in immunopeptidomic mass spectrometry identifications, they have been reported to achieve undesirably low sensitivities or high false positive rates as a result of the hugely inflated search space caused b...
Autores principales: | Zhang, Le, Liu, Geng, Hou, Guixue, Xiang, Haitao, Zhang, Xi, Huang, Ying, Zhang, Xiuqing, Li, Bo, Lee, Leo J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025654/ https://www.ncbi.nlm.nih.gov/pubmed/35454168 http://dx.doi.org/10.3390/biom12040579 |
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