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Efficacy of Nanofiber Sheets Incorporating Lenvatinib in a Hepatocellular Carcinoma Xenograft Model

Lenvatinib has a high response rate in unresectable advanced hepatocellular carcinoma (HCC). In this study, we investigated whether lenvatinib-incorporating poly(ε-caprolactone) sheets (lenvatinib sheets) as a drug delivery system (DDS) exerted antitumor effects in a murine HCC model. The lenvatinib...

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Detalles Bibliográficos
Autores principales: Yoshida, Terufumi, Kaibori, Masaki, Fujisawa, Nanami, Ishizuka, Mariko, Sumiyama, Fusao, Hatta, Masahiko, Kosaka, Hisashi, Matsui, Kosuke, Suzuki, Kensuke, Akama, Tomoya O., Katano, Tayo, Yoshii, Kengo, Ebara, Mitsuhiro, Sekimoto, Mitsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025678/
https://www.ncbi.nlm.nih.gov/pubmed/35458072
http://dx.doi.org/10.3390/nano12081364