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Glucagon-like Peptide-1 Secretion Is Inhibited by Lysophosphatidic Acid

Glucagon-like peptide-1 (GLP-1) potentiates glucose-stimulated insulin secretion (GSIS). While dozens of compounds stimulate GLP-1 secretion, few inhibit. Reduced GLP-1 secretion and impaired GSIS occur in chronic inflammation. Lysophosphatidic acids (LPAs) are bioactive phospholipids elevated in in...

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Detalles Bibliográficos
Autores principales: Fernandes, Maria F., Tomczewski, Michelle V., Duncan, Robin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025735/
https://www.ncbi.nlm.nih.gov/pubmed/35456981
http://dx.doi.org/10.3390/ijms23084163