Developing CRISPR/Cas9-Mediated Fluorescent Reporter Human Pluripotent Stem-Cell Lines for High-Content Screening

Application of the CRISPR/Cas9 system to knock in fluorescent proteins to endogenous genes of interest in human pluripotent stem cells (hPSCs) has the potential to facilitate hPSC-based disease modeling, drug screening, and optimization of transplantation therapy. To evaluate the capability of fluor...

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Detalles Bibliográficos
Autores principales: Vojnits, Kinga, Nakanishi, Mio, Porras, Deanna, Kim, Yeonjoon, Feng, Zhuohang, Golubeva, Diana, Bhatia, Mick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025795/
https://www.ncbi.nlm.nih.gov/pubmed/35458632
http://dx.doi.org/10.3390/molecules27082434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025795/
https://www.ncbi.nlm.nih.gov/pubmed/35458632
http://dx.doi.org/10.3390/molecules27082434

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