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Dietary Choline Alleviates High-Fat Diet-Induced Hepatic Lipid Dysregulation via UPRmt Modulated by SIRT3-Mediated mtHSP70 Deacetylation

The mitochondrial unfolded protein response (UPRmt) is known as a conservative mechanism in response to mitochondrial dysfunction. Thus, based on UPRmt, this study was conducted to determine the mechanism of a high-fat diet (HFD) inducing mitochondrial dysfunction and its role in stimulating hepatic...

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Detalles Bibliográficos
Autores principales: Song, Yu-Feng, Zheng, Hua, Luo, Zhi, Hogstrand, Christer, Bai, Zhen-Yu, Wei, Xiao-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025889/
https://www.ncbi.nlm.nih.gov/pubmed/35457022
http://dx.doi.org/10.3390/ijms23084204