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Dietary Choline Alleviates High-Fat Diet-Induced Hepatic Lipid Dysregulation via UPRmt Modulated by SIRT3-Mediated mtHSP70 Deacetylation
The mitochondrial unfolded protein response (UPRmt) is known as a conservative mechanism in response to mitochondrial dysfunction. Thus, based on UPRmt, this study was conducted to determine the mechanism of a high-fat diet (HFD) inducing mitochondrial dysfunction and its role in stimulating hepatic...
Autores principales: | Song, Yu-Feng, Zheng, Hua, Luo, Zhi, Hogstrand, Christer, Bai, Zhen-Yu, Wei, Xiao-Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025889/ https://www.ncbi.nlm.nih.gov/pubmed/35457022 http://dx.doi.org/10.3390/ijms23084204 |
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