Specific Interaction of DARPin with HIV-1 CA(NTD) Disturbs the Distribution of Gag, RNA Packaging, and Tetraspanin Remodelling in the Membrane

A designed repeat scaffold protein (Ank(GAG)1D4) recognizing the human immunodeficiency virus-1 (HIV-1) capsid (CA) was formerly established with antiviral assembly. Here, we investigated the molecular mechanism of Ank(GAG)1D4 function during the late stages of the HIV-1 replication cycle. By applyi...

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Detalles Bibliográficos
Autores principales: Moonmuang, Sutpirat, Maniratanachote, Rawiwan, Chetprayoon, Paninee, Sornsuwan, Kanokporn, Thongkum, Weeraya, Chupradit, Koollawat, Tayapiwatana, Chatchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025900/
https://www.ncbi.nlm.nih.gov/pubmed/35458554
http://dx.doi.org/10.3390/v14040824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025900/
https://www.ncbi.nlm.nih.gov/pubmed/35458554
http://dx.doi.org/10.3390/v14040824

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