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Specific Interaction of DARPin with HIV-1 CA(NTD) Disturbs the Distribution of Gag, RNA Packaging, and Tetraspanin Remodelling in the Membrane
A designed repeat scaffold protein (Ank(GAG)1D4) recognizing the human immunodeficiency virus-1 (HIV-1) capsid (CA) was formerly established with antiviral assembly. Here, we investigated the molecular mechanism of Ank(GAG)1D4 function during the late stages of the HIV-1 replication cycle. By applyi...
Autores principales: | Moonmuang, Sutpirat, Maniratanachote, Rawiwan, Chetprayoon, Paninee, Sornsuwan, Kanokporn, Thongkum, Weeraya, Chupradit, Koollawat, Tayapiwatana, Chatchai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025900/ https://www.ncbi.nlm.nih.gov/pubmed/35458554 http://dx.doi.org/10.3390/v14040824 |
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