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Tet1 Suppresses p21 to Ensure Proper Cell Cycle Progression in Embryonic Stem Cells

Ten eleven translocation 1 (Tet1) is a DNA dioxygenase that promotes DNA demethylation by oxidizing 5-methylcytosine. It can also partner with chromatin-activating and repressive complexes to regulate gene expressions independent of its enzymatic activity. Tet1 is highly expressed in embryonic stem...

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Detalles Bibliográficos
Autores principales: Chrysanthou, Stephanie, Flores, Julio C., Dawlaty, Meelad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025953/
https://www.ncbi.nlm.nih.gov/pubmed/35456045
http://dx.doi.org/10.3390/cells11081366