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Tet1 Suppresses p21 to Ensure Proper Cell Cycle Progression in Embryonic Stem Cells
Ten eleven translocation 1 (Tet1) is a DNA dioxygenase that promotes DNA demethylation by oxidizing 5-methylcytosine. It can also partner with chromatin-activating and repressive complexes to regulate gene expressions independent of its enzymatic activity. Tet1 is highly expressed in embryonic stem...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025953/ https://www.ncbi.nlm.nih.gov/pubmed/35456045 http://dx.doi.org/10.3390/cells11081366 |