Inactivation of a New Potassium Channel Increases Rifampicin Resistance and Induces Collateral Sensitivity to Hydrophilic Antibiotics in Mycobacterium smegmatis

Rifampicin is a critical first-line antibiotic for treating mycobacterial infections such as tuberculosis, one of the most serious infectious diseases worldwide. Rifampicin resistance in mycobacteria is mainly caused by mutations in the rpoB gene; however, some rifampicin-resistant strains showed no...

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Detalles Bibliográficos
Autores principales: Do, Thi Thuy, Rodríguez-Beltran, Jerónimo, Cebrián-Sastre, Esmeralda, Rodríguez-Rojas, Alexandro, Castañeda-García, Alfredo, Blázquez, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025972/
https://www.ncbi.nlm.nih.gov/pubmed/35453260
http://dx.doi.org/10.3390/antibiotics11040509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025972/
https://www.ncbi.nlm.nih.gov/pubmed/35453260
http://dx.doi.org/10.3390/antibiotics11040509

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