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Limitations of Trifluoromethylbenzoimidazolylbenzoic Acid as a Chiral Derivatizing Agent to Assign Absolute Configuration for β-Chiral Aminoalcohols

[Image: see text] Axially chiral 2-(2-(trifluoromethyl)-1H-benzo[d]imidazole-1-yl)benzoic acid (TBBA) was used as a chiral derivatizing agent to evaluate the limits of absolute configuration assignment for β-chiral aminoalcohols. Seven Boc-aminoalcohols and eight variously N-substituted (S)-phenylgl...

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Detalles Bibliográficos
Autores principales: Kriegelstein, Michal, Profous, David, Přibylka, Adam, Lyčka, Antonín, Cankař, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9025982/
https://www.ncbi.nlm.nih.gov/pubmed/35474810
http://dx.doi.org/10.1021/acsomega.1c07234