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Extracellular nucleoprotein exacerbates influenza virus pathogenesis by activating Toll-like receptor 4 and the NLRP3 inflammasome

Host immune responses, such as those initiated by pattern recognition receptor (PRR) activation, are important for viral clearance and pathogenesis. However, little is known about the interactions of viral proteins with surface PRRs or, more importantly, the association of innate immune activation w...

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Detalles Bibliográficos
Autores principales: Kim, Chang-Ung, Jeong, Yu-Jin, Lee, Pureum, Lee, Moo-Seung, Park, Jong-Hwan, Kim, Young-Sang, Kim, Doo-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026019/
https://www.ncbi.nlm.nih.gov/pubmed/35459853
http://dx.doi.org/10.1038/s41423-022-00862-5