Enhancing the Anticancer Potential of Targeting Tumor-Associated Metalloenzymes via VEGFR Inhibition by New Triazolo[4,3-a]pyrimidinone Acyclo C-Nucleosides Multitarget Agents

The role of metalloenzymes in tumor progression had broadened their application in cancer therapy. Of these, MMPs and CAs are validated druggable targets that share some pivotal signaling pathways. The majority of MMPs or CAs inhibitors are designed as single-target agents. Despite their transient e...

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Detalles Bibliográficos
Autores principales: Abd Al Moaty, Mohamed Nabil, El Ashry, El Sayed Helmy, Awad, Laila Fathy, Ibrahim, Nihal Ahmed, Abu-Serie, Marwa Muhammad, Barakat, Assem, Altowyan, Mezna Saleh, Teleb, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026109/
https://www.ncbi.nlm.nih.gov/pubmed/35458618
http://dx.doi.org/10.3390/molecules27082422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026109/
https://www.ncbi.nlm.nih.gov/pubmed/35458618
http://dx.doi.org/10.3390/molecules27082422

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