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Natural and Synthetic Sortase A Substrates Are Processed by Staphylococcus aureus via Different Pathways

[Image: see text] Endogenous Staphylococcus aureus sortase A (SrtA) covalently incorporates cell wall anchored proteins equipped with a SrtA recognition motif (LPXTG) via a lipid II-dependent pathway into the staphylococcal peptidoglycan layer. Previously, we found that the endogenous S. aureus SrtA...

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Detalles Bibliográficos
Autores principales: Hansenová Maňásková, Silvie, Nazmi, Kamran, van’t Hof, Wim, van Belkum, Alex, Kaman, Wendy E., Martin, Nathaniel I., Veerman, Enno C. I., Bikker, Floris J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026250/
https://www.ncbi.nlm.nih.gov/pubmed/35319881
http://dx.doi.org/10.1021/acs.bioconjchem.2c00012