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Synergistic Experimental and Computational Investigation of the Bioorthogonal Reactivity of Substituted Aryltetrazines

[Image: see text] Tetrazines (Tz) have been applied as bioorthogonal agents for various biomedical applications, including pretargeted imaging approaches. In radioimmunoimaging, pretargeting increases the target-to-background ratio while simultaneously reducing the radiation burden. We have recently...

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Detalles Bibliográficos
Autores principales: Battisti, Umberto M., García-Vázquez, Rocío, Svatunek, Dennis, Herrmann, Barbara, Löffler, Andreas, Mikula, Hannes, Herth, Matthias Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026259/
https://www.ncbi.nlm.nih.gov/pubmed/35290735
http://dx.doi.org/10.1021/acs.bioconjchem.2c00042