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Resolving the Multidecade-Long Mystery in MoaA Radical SAM Enzyme Reveals New Opportunities to Tackle Human Health Problems

[Image: see text] MoaA is one of the most conserved radical S-adenosyl-l-methionine (SAM) enzymes, and is found in most organisms in all three kingdoms of life. MoaA contributes to the biosynthesis of molybdenum cofactor (Moco), a redox enzyme cofactor used in various enzymes such as purine and sulf...

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Detalles Bibliográficos
Autores principales: Yokoyama, Kenichi, Li, Di, Pang, Haoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026282/
https://www.ncbi.nlm.nih.gov/pubmed/35480226
http://dx.doi.org/10.1021/acsbiomedchemau.1c00046