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The Role of SLC22A1 and Genomic Ancestry on Toxicity during Treatment in Children with Acute Lymphoblastic Leukemia of the Amazon Region

In Brazil, Acute lymphoid leukemia (ALL) is the leading cause of cancer deaths in children and adolescents. Treatment toxicity is one of the reasons for stopping chemotherapy. Amerindian genomic ancestry is an important factor for this event due to fluctuations in frequencies of genetic variants, as...

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Detalles Bibliográficos
Autores principales: Fernandes, Sweny de S. M., Leitão, Luciana P. C., Cohen-Paes, Amanda de N., Gellen, Laura P. A., Pastana, Lucas F., de Carvalho, Darlen C., Modesto, Antônio A. C., da Costa, Ana C. A., Wanderley, Alayde V., de Lima, Carlos H. V., Pereira, Esdras E. B., Fernandes, Marianne R., Burbano, Rommel M. R., de Assumpção, Paulo P., dos Santos, Sidney E. B., dos Santos, Ney P. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026289/
https://www.ncbi.nlm.nih.gov/pubmed/35456416
http://dx.doi.org/10.3390/genes13040610