Mechano Growth Factor Accelerates ACL Repair and Improves Cell Mobility of Mechanically Injured Human ACL Fibroblasts by Targeting Rac1-PAK1/2 and RhoA-ROCK1 Pathways

Exceeded mechanical stress leads to a sublethal injury to anterior cruciate ligament (ACL) fibroblasts, and it will hinder cell mobility and ACL regeneration, and even induce osteoarthritis. The mechano growth factor (MGF) could be responsible for mechanical stress and weakening its negative effects...

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Detalles Bibliográficos
Autores principales: Sha, Yongqiang, Zhang, Beibei, Chen, Liping, Hong, Huhai, Chi, Qingjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026312/
https://www.ncbi.nlm.nih.gov/pubmed/35457148
http://dx.doi.org/10.3390/ijms23084331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026312/
https://www.ncbi.nlm.nih.gov/pubmed/35457148
http://dx.doi.org/10.3390/ijms23084331

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