Design, Synthesis, and Cytotoxicity and Topoisomerase I/IIα Inhibition Activity of Pyrazolo[4,3-f]quinoline Derivatives

With the several targets of cancer treatment, inhibition of DNA topoisomerase activity is one of the well-known focuses in cancer chemotherapy. Here, we describe the design and synthesis of a novel series of pyrazolo[4,3-f]quinolines with potential anticancer/topoisomerase inhibition activity. Forty...

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Detalles Bibliográficos
Autores principales: Chaudhary, Chhabi Lal, Ko, Seungyun, Lee, Chaerim, Kim, Yerin, Jung, Chanhyun, Hyun, Soonsil, Kwon, Youngjoo, Kang, Jong-Soon, Jung, Jae-Kyung, Lee, Heesoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026320/
https://www.ncbi.nlm.nih.gov/pubmed/35455396
http://dx.doi.org/10.3390/ph15040399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026320/
https://www.ncbi.nlm.nih.gov/pubmed/35455396
http://dx.doi.org/10.3390/ph15040399

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