Cargando…

Apoptotic and DNA Damage Effect of 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose in Cisplatin-Resistant Non-Small Lung Cancer Cells via Phosphorylation of H(2)AX, CHK2 and p53

Herein, the apoptotic mechanism of 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose (PGG) was examined in cisplatin-resistant lung cancer cells. PGG significantly reduced viability; increased sub-G1 accumulation and the number of terminal deoxynucleotidyl transferase (TdT) dUTP Nick-End Labeling (TUNEL)-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ji-Hyun, Im, Eunji, Lee, Jihyun, Lee, Hyo-Jung, Sim, Deok Yong, Park, Ji Eon, Ahn, Chi-Hoon, Kwon, Hyeon Hee, Shim, Bum Sang, Kim, Bonglee, Kim, Sung-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026497/ https://www.ncbi.nlm.nih.gov/pubmed/35456022 http://dx.doi.org/10.3390/cells11081343

Ejemplares similares

The Longevity Properties of 1,2,3,4,6-Penta-O-Galloyl-β-D-Glucose from Curcuma longa in Caenorhabditis elegans
por: Ahn, Dalrae, et al.
Publicado: (2013)

Penta-1,2,3,4,6-O-Galloyl-β-d-Glucose Inhibits UVB-Induced Photoaging by Targeting PAK1 and JNK1
por: Kim, Ji-An, et al.
Publicado: (2019)

In vitro anti-hepatocellular carcinogenesis of 1,2,3,4,6-Penta-O-galloyl-β-D-glucose
por: Jiang, Yu-han, et al.
Publicado: (2023)

A Novel Small Molecule 1,2,3,4,6-penta-O-galloyl-α-D-glucopyranose Mimics the Antiplatelet Actions of Insulin
por: Perveen, Rehana, et al.
Publicado: (2011)

Inhibition of Rabies Virus by 1,2,3,4,6-Penta-O-galloyl-β-d-Glucose Involves mTOR-Dependent Autophagy
por: Tu, Zhongzhong, et al.
Publicado: (2018)

1,2,3,4,6-Penta-O-Galloyl-Beta-D-Glucopyranoside Inhibits Proliferation of Multiple Myeloma Cells Accompanied with Suppression of MYC Expression
por: Tseeleesuren, Duurenjargal, et al.
Publicado: (2018)

Induction of GNMT by 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranoside through proteasome-independent MYC downregulation in hepatocellular carcinoma
por: Kant, Rajni, et al.
Publicado: (2019)

1,2,3,4,6-Penta-O-galloyl-d-glucose Interrupts the Early Adipocyte Lifecycle and Attenuates Adiposity and Hepatic Steatosis in Mice with Diet-Induced Obesity
por: Sathyanarayana, Ashish Rao, et al.
Publicado: (2022)

1,2,3,4,6‐Penta‐O‐galloyl‐β‐d‐glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II‐induced hypertension
por: Mikolajczyk, Tomasz P., et al.
Publicado: (2019)

Molecular docking analysis of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets
por: Dharmalingam, Karthick, et al.
Publicado: (2021)

1,2,3,4,6-Penta-O-galloyl-β-D-glucose Inhibits CD44v3, a cancer stem cell marker, by regulating its transcription factor, in human pancreatic cancer cell line
por: Kim, Eun-Young, et al.
Publicado: (2022)

Identification of 1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranoside as a Glycine N-Methyltransferase Enhancer by High-Throughput Screening of Natural Products Inhibits Hepatocellular Carcinoma
por: Kant, Rajni, et al.
Publicado: (2016)

p53-Dependent Apoptotic Effect of Puromycin via Binding of Ribosomal Protein L5 and L11 to MDM2 and Its Combination Effect with RITA or Doxorubicin
por: Jung, Ji Hoon, et al.
Publicado: (2019)

The Apoptotic and Anti-Warburg Effects of Brassinin in PC-3 Cells via Reactive Oxygen Species Production and the Inhibition of the c-Myc, SIRT1, and β-Catenin Signaling Axis
por: Kwon, Hyeon Hee, et al.
Publicado: (2023)

UBE2M Drives Hepatocellular Cancer Progression as a p53 Negative Regulator by Binding to MDM2 and Ribosomal Protein L11
por: Kim, Ju-Ha, et al.
Publicado: (2021)

1,2,3,4,6‑penta‑O‑galloyl‑β‑D‑glucose alleviates inflammation and oxidative stress in diabetic nephropathy rats through MAPK/NF‑κB and ERK/Nrf2/HO‑1 signaling pathways
por: Wang, Dong, et al.
Publicado: (2022)

Recent Advances in Nanotechnology with Nano-Phytochemicals: Molecular Mechanisms and Clinical Implications in Cancer Progression
por: Kim, Bonglee, et al.
Publicado: (2021)

Inhibition of STAT3/PD-L1 and Activation of miR193a-5p Are Critically Involved in Apoptotic Effect of Compound K in Prostate Cancer Cells
por: Lee, Jae-Hee, et al.
Publicado: (2021)

Molecular docking analysis of penta-galloyl-glucose with VEGF signaling molecules
por: Dharmalingam, Karthick, et al.
Publicado: (2021)

CNOT2 Is Critically Involved in Atorvastatin Induced Apoptotic and Autophagic Cell Death in Non-Small Cell Lung Cancers
por: Lee, Jihyun, et al.
Publicado: (2019)

Inhibition of Wnt3a/FOXM1/β-Catenin Axis and Activation of GSK3β and Caspases are Critically Involved in Apoptotic Effect of Moracin D in Breast Cancers
por: Hwang, Sung Min, et al.
Publicado: (2018)

Triggering of Suicidal Erythrocyte Death by Penta-O-galloyl-β-d-glucose
por: Alzoubi, Kousi, et al.
Publicado: (2013)

Suppression of STAT3 Phosphorylation and RelA/p65 Acetylation Mediated by MicroRNA134 Plays a Pivotal Role in the Apoptotic Effect of Lambertianic Acid
por: Sim, Deok Yong, et al.
Publicado: (2019)

Farnesiferol C Induces Apoptosis in Chronic Myelogenous Leukemia Cells as an Imatinib Sensitizer via Caspase Activation and HDAC (Histone Deacetylase) Inactivation
por: Jung, Ji Hoon, et al.
Publicado: (2019)

γH2AX and Chk1 phosphorylation as predictive pharmacodynamic biomarkers of Chk1 inhibitor-chemotherapy combination treatments
por: Rawlinson, Rebecca, et al.
Publicado: (2014)

Sulphated penta-galloyl glucopyranoside (SPGG) is glycosaminoglycan mimetic allosteric inhibitor of cathepsin G
por: Al-Horani, Rami A, et al.
Publicado: (2023)

Potential Antimicrobial Activity of Galloyl-Flavonoid Glycosides From Woodfordia uniflora Against Methicillin-Resistant Staphylococcus aureus
por: Yu, Jae Sik, et al.
Publicado: (2021)

miR193a-5p Mediated ZNF746 and c-Myc Signaling Axis Is Critically Involved in Morusin Induced Apoptosis in Colorectal Cancer Cells
por: Park, Woon-Yi, et al.
Publicado: (2021)

The Antitumor Effect of Cinnamaldehyde Derivative CB-PIC in Hepatocellular Carcinoma Cells via Inhibition of Pyruvate and STAT3 Signaling
por: Kim, Hyungjin, et al.
Publicado: (2022)

UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation
por: Sun, Jingyuan, et al.
Publicado: (2020)

Intraluminal infusion of Penta-Galloyl Glucose reduces abdominal aortic aneurysm development in the elastase rat model
por: Schack, Asbjørn Sune, et al.
Publicado: (2020)

Colocalization of MID1IP1 and c-Myc is Critically Involved in Liver Cancer Growth via Regulation of Ribosomal Protein L5 and L11 and CNOT2
por: Jung, Ji Hoon, et al.
Publicado: (2020)

De novo phosphorylation of H2AX by WSTF regulates transcription-coupled homologous recombination repair
por: Ji, Jae-Hoon, et al.
Publicado: (2019)

Antitumor Effect of Morusin via G1 Arrest and Antiglycolysis by AMPK Activation in Hepatocellular Cancer
por: Cho, Ah-Reum, et al.
Publicado: (2021)

Enhanced H2AX Phosphorylation, DNA Replication Fork Arrest, and Cell Death in the Absence of Chk1
por: Gagou, Mary E., et al.
Publicado: (2010)

Chk1, Chk2, is the amplifier on?
por: Dove, Alan W.
Publicado: (2001)

Galloyl-RGD as a new cosmetic ingredient
por: Park, Dae-Hun, et al.
Publicado: (2014)

Photoprotective Potential of Penta-O-Galloyl-β-DGlucose by Targeting NF-κB and MAPK Signaling in UVB Radiation-Induced Human Dermal Fibroblasts and Mouse Skin
por: Kim, Byung-Hak, et al.
Publicado: (2015)

1,2,3,4,6-Penta-O-galloylglucose within Galla Chinensis Inhibits Human LDH-A and Attenuates Cell Proliferation in MDA-MB-231 Breast Cancer Cells
por: Deiab, Shihab, et al.
Publicado: (2015)

Genome-wide profiles of H2AX and γ-H2AX differentiate endogenous and exogenous DNA damage hotspots in human cells
por: Seo, Jungmin, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_9hmh69am27c3vpmkbjte2knrie