A computational pipeline to visualize DNA-protein binding states using dSMF data

Here, we present a pipeline to map states of protein-binding DNA in vivo. Our pipeline infers as well as quantifies cooperative binding. Using dual-enzyme single-molecule footprinting (dSMF) data, we show how our workflow identifies binding states at an enhancer in Drosophila S2 cells. Data from cel...

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Detalles Bibliográficos
Autores principales: Rao, Satyanarayan, Ramachandran, Srinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026571/
https://www.ncbi.nlm.nih.gov/pubmed/35463472
http://dx.doi.org/10.1016/j.xpro.2022.101299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026571/
https://www.ncbi.nlm.nih.gov/pubmed/35463472
http://dx.doi.org/10.1016/j.xpro.2022.101299

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