Rapid establishment of human colonic organoid knockout lines

Human colonic organoids derived from biopsy or autopsy tissues are a vital tool to study mucosal homeostasis, model colonic diseases, and develop therapeutics. Rapid and reliable generation of knockout organoid lines from multiple donors enables analysis of specific gene functions. Here, we report p...

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Detalles Bibliográficos
Autores principales: Gu, Wei, Colarusso, Jonathan L., Dame, Michael K., Spence, Jason R., Zhou, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026586/
https://www.ncbi.nlm.nih.gov/pubmed/35463469
http://dx.doi.org/10.1016/j.xpro.2022.101308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026586/
https://www.ncbi.nlm.nih.gov/pubmed/35463469
http://dx.doi.org/10.1016/j.xpro.2022.101308

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