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Synthetic acid stress-tolerance modules improve growth robustness and lysine productivity of industrial Escherichia coli in fermentation at low pH

BACKGROUND: During fermentation, industrial microorganisms encounter multiple stresses that inhibit cell growth and decrease fermentation yields, in particular acid stress, which is due to the accumulation of acidic metabolites in the fermentation medium. Although the addition of a base to the mediu...

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Detalles Bibliográficos
Autores principales: Yao, Xurong, Liu, Peng, Chen, Bo, Wang, Xiaoyan, Tao, Fei, Lin, Zhanglin, Yang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026648/
https://www.ncbi.nlm.nih.gov/pubmed/35459210
http://dx.doi.org/10.1186/s12934-022-01795-4