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hMSH5 Regulates NHEJ and Averts Excessive Nucleotide Alterations at Repair Joints
Inappropriate repair of DNA double-strand breaks (DSBs) leads to genomic instability, cell death, or malignant transformation. Cells minimize these detrimental effects by selectively activating suitable DSB repair pathways in accordance with their underlying cellular context. Here, we report that hM...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026759/ https://www.ncbi.nlm.nih.gov/pubmed/35456479 http://dx.doi.org/10.3390/genes13040673 |