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hMSH5 Regulates NHEJ and Averts Excessive Nucleotide Alterations at Repair Joints

Inappropriate repair of DNA double-strand breaks (DSBs) leads to genomic instability, cell death, or malignant transformation. Cells minimize these detrimental effects by selectively activating suitable DSB repair pathways in accordance with their underlying cellular context. Here, we report that hM...

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Detalles Bibliográficos
Autores principales: Al-Soodani, Aneesa T., Wu, Xiling, Kelp, Nicole C., Brown, Alexander J., Roberts, Steven A., Her, Chengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026759/
https://www.ncbi.nlm.nih.gov/pubmed/35456479
http://dx.doi.org/10.3390/genes13040673