InsuLock: A Weakly Supervised Learning Approach for Accurate Insulator Prediction, and Variant Impact Quantification

Mapping chromatin insulator loops is crucial to investigating genome evolution, elucidating critical biological functions, and ultimately quantifying variant impact in diseases. However, chromatin conformation profiling assays are usually expensive, time-consuming, and may report fuzzy insulator ann...

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Detalles Bibliográficos
Autores principales: Srinivasan, Shushrruth Sai, Gong, Yanwen, Xu, Siwei, Hwang, Ahyeon, Xu, Min, Girgenti, Matthew J., Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026820/
https://www.ncbi.nlm.nih.gov/pubmed/35456427
http://dx.doi.org/10.3390/genes13040621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026820/
https://www.ncbi.nlm.nih.gov/pubmed/35456427
http://dx.doi.org/10.3390/genes13040621

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