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Advances in the Development of SARS-CoV-2 Mpro Inhibitors

Since the outbreak of COVID-19, one of the strategies used to search for new drugs has been to find inhibitors of the main protease (Mpro) of the virus SARS-CoV-2. Initially, previously reported inhibitors of related proteases such as the main proteases of SARS-CoV and MERS-CoV were tested. A huge e...

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Detalles Bibliográficos
Autores principales: Agost-Beltrán, Laura, de la Hoz-Rodríguez, Sergio, Bou-Iserte, Lledó, Rodríguez, Santiago, Fernández-de-la-Pradilla, Adrián, González, Florenci V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026863/
https://www.ncbi.nlm.nih.gov/pubmed/35458721
http://dx.doi.org/10.3390/molecules27082523