Discovery of a Novel Inhibitor Structure of Mycobacterium tuberculosis Isocitrate Lyase

Tuberculosis remains a global threat to public health, and dormant Mycobacterium tuberculosis leads to long-term medication that is harmful to the human body. M. tuberculosis isocitrate lyase (MtICL), which is absent in host cells, is a key rate-limiting enzyme of the glyoxylic acid cycle and is ess...

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Detalles Bibliográficos
Autores principales: Duan, Changyuan, Jiang, Qihua, Jiang, Xue, Zeng, Hongwei, Wu, Qiaomin, Yu, Yang, Yang, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026967/
https://www.ncbi.nlm.nih.gov/pubmed/35458645
http://dx.doi.org/10.3390/molecules27082447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026967/
https://www.ncbi.nlm.nih.gov/pubmed/35458645
http://dx.doi.org/10.3390/molecules27082447

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