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Discovery of a Novel Inhibitor Structure of Mycobacterium tuberculosis Isocitrate Lyase

Tuberculosis remains a global threat to public health, and dormant Mycobacterium tuberculosis leads to long-term medication that is harmful to the human body. M. tuberculosis isocitrate lyase (MtICL), which is absent in host cells, is a key rate-limiting enzyme of the glyoxylic acid cycle and is ess...

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Detalles Bibliográficos
Autores principales:	Duan, Changyuan, Jiang, Qihua, Jiang, Xue, Zeng, Hongwei, Wu, Qiaomin, Yu, Yang, Yang, Xiaolan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9026967/ https://www.ncbi.nlm.nih.gov/pubmed/35458645 http://dx.doi.org/10.3390/molecules27082447

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