Genetic Background of Polycythemia Vera

Polycythemia vera belongs to myeloproliferative neoplasms, essentially by affecting the erythroblastic lineage. JAK2 alterations have emerged as major driver mutations triggering PV-phenotype with the V617F mutation detected in nearly 98% of cases. That’s why JAK2 targeting therapeutic strategies ha...

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Detalles Bibliográficos
Autores principales: Regimbeau, Mathilde, Mary, Romain, Hermetet, François, Girodon, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027017/
https://www.ncbi.nlm.nih.gov/pubmed/35456443
http://dx.doi.org/10.3390/genes13040637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027017/
https://www.ncbi.nlm.nih.gov/pubmed/35456443
http://dx.doi.org/10.3390/genes13040637

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