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CDK16 promotes the progression and metastasis of triple-negative breast cancer by phosphorylating PRC1
BACKGROUND: Cyclin-dependent kinase 16 (CDK16) is an atypical PCTAIRE kinase, and its activity is dependent on the Cyclin Y (CCNY) family. Ccnys have been reported to regulate mammary stem cell activity and mammary gland development, and CCNY has been recognized as an oncoprotein in various cancers,...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027050/ https://www.ncbi.nlm.nih.gov/pubmed/35449080 http://dx.doi.org/10.1186/s13046-022-02362-w |