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CDK16 promotes the progression and metastasis of triple-negative breast cancer by phosphorylating PRC1

BACKGROUND: Cyclin-dependent kinase 16 (CDK16) is an atypical PCTAIRE kinase, and its activity is dependent on the Cyclin Y (CCNY) family. Ccnys have been reported to regulate mammary stem cell activity and mammary gland development, and CCNY has been recognized as an oncoprotein in various cancers,...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Li, Jinpeng, Xu, Liming, Wei, Wei, Cheng, Anyi, Zhang, Lingxian, Zhang, Mengna, Wu, Gaosong, Cai, Cheguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027050/
https://www.ncbi.nlm.nih.gov/pubmed/35449080
http://dx.doi.org/10.1186/s13046-022-02362-w