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Frequency of the Dopamine Receptor D3 (rs6280) vs. Opioid Receptor µ1 (rs1799971) Polymorphic Risk Alleles in Patients with Opioid Use Disorder: A Preponderance of Dopaminergic Mechanisms?

While opioids are a powerful class of drugs that inhibit transmission of pain signals, their use is tarnished by the current epidemic of opioid use disorder (OUD) and overdose deaths. Notwithstanding published reports, there remain gaps in our knowledge of opioid receptor mechanisms and their role i...

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Detalles Bibliográficos
Autores principales: Gondré-Lewis, Marjorie C., Elman, Igor, Alim, Tanya, Chapman, Edwin, Settles-Reaves, Beverlyn, Galvao, Carine, Gold, Mark S., Baron, David, Kazmi, Shan, Gardner, Eliot, Gupta, Ashim, Dennen, Catherine, Blum, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027142/
https://www.ncbi.nlm.nih.gov/pubmed/35453620
http://dx.doi.org/10.3390/biomedicines10040870