A New Hypothetical Concept in Metabolic Understanding of Cardiac Fibrosis: Glycolysis Combined with TGF-β and KLF5 Signaling

The accumulation of fibrosis in cardiac tissues is one of the leading causes of heart failure. The principal cellular effectors in cardiac fibrosis are activated fibroblasts and myofibroblasts, which serve as the primary source of matrix proteins. TGF-β signaling pathways play a prominent role in ca...

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Detalles Bibliográficos
Autores principales: Methatham, Thanachai, Nagai, Ryozo, Aizawa, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027193/
https://www.ncbi.nlm.nih.gov/pubmed/35457114
http://dx.doi.org/10.3390/ijms23084302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027193/
https://www.ncbi.nlm.nih.gov/pubmed/35457114
http://dx.doi.org/10.3390/ijms23084302

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