First-in-Human Study of [(68)Ga]Ga-NODAGA-E[c(RGDyK)](2) PET for Integrin α(v)β(3) Imaging in Patients with Breast Cancer and Neuroendocrine Neoplasms: Safety, Dosimetry and Tumor Imaging Ability

Arginine-Glycine-Aspartate (RGD)-recognizing cell surface integrins are involved in tumor growth, invasiveness/metastases, and angiogenesis, and are therefore an attractive treatment target in cancers. The subtype integrin α(v)β(3) is upregulated on endothelial cells during angiogenesis and on tumor...

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Detalles Bibliográficos
Autores principales: Clausen, Malene Martini, Carlsen, Esben Andreas, Christensen, Camilla, Madsen, Jacob, Brandt-Larsen, Malene, Klausen, Thomas Levin, Holm, Søren, Loft, Annika, Berthelsen, Anne Kiil, Kroman, Niels, Knigge, Ulrich, Kjaer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027224/
https://www.ncbi.nlm.nih.gov/pubmed/35453899
http://dx.doi.org/10.3390/diagnostics12040851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027224/
https://www.ncbi.nlm.nih.gov/pubmed/35453899
http://dx.doi.org/10.3390/diagnostics12040851

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