Isatin Counteracts Diethylnitrosamine/2-Acetylaminofluorene-Induced Hepatocarcinogenesis in Male Wistar Rats by Upregulating Anti-Inflammatory, Antioxidant, and Detoxification Pathways

Hepatocellular carcinoma (HCC) represents around 85% of all known types of liver cancers and is estimated to be the fifth most common cause of cancer-related death worldwide. The current study assessed the preventive efficacy of isatin on diethylnitrosamine (DENA)/2-acetylaminofluorene (2-AAF)-induc...

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Detalles Bibliográficos
Autores principales: Tawfik, Nagwa G., Mohamed, Wafaa R., Mahmoud, Hanan S., Alqarni, Mohammed A., Naguib, Ibrahim A., Fahmy, Alzhraa M., Ahmed, Osama M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027254/
https://www.ncbi.nlm.nih.gov/pubmed/35453384
http://dx.doi.org/10.3390/antiox11040699