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The MST1R/RON Tyrosine Kinase in Cancer: Oncogenic Functions and Therapeutic Strategies

SIMPLE SUMMARY: MST1R/RON receptor tyrosine kinase is a highly conserved transmembrane protein present on epithelial cells, macrophages, and recently identified in a T-cell subset. RON activation attenuates inflammation in healthy tissue. Interestingly, it is overexpressed in several epithelial neop...

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Detalles Bibliográficos
Autores principales: Cazes, Alex, Childers, Betzaira G., Esparza, Edgar, Lowy, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027306/
https://www.ncbi.nlm.nih.gov/pubmed/35454943
http://dx.doi.org/10.3390/cancers14082037