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Cannabinol Inhibits Cellular Proliferation, Invasion, and Angiogenesis of Neuroblastoma via Novel miR-34a/tRiMetF31/PFKFB3 Axis

SIMPLE SUMMARY: The prognosis of high-risk neuroblastoma is poor due to its high relapse rate. To date, no effective treatment for this disease has been developed. In this study, we utilized two neuroblastoma cell lines (IMR-5 and SK-N-AS) as a model system to explore the effects of cannabinol (CBN)...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Li, Dongping, Cherkasova, Viktoriia, Gerasymchuk, Marta, Narendran, Aru, Kovalchuk, Igor, Kovalchuk, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027424/
https://www.ncbi.nlm.nih.gov/pubmed/35454815
http://dx.doi.org/10.3390/cancers14081908