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Nuclear respiratory factor 1 promotes the growth of liver hepatocellular carcinoma cells via E2F1 transcriptional activation

BACKGROUND: Recent studies have shown that functional mitochondria are essential for cancer cells. Nuclear respiratory factor 1 (NRF1) is a transcription factor that activates mitochondrial biogenesis and the expression of the respiratory chain, but little is known about its role and underlying mech...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Wan, Baolan, Zhang, Xiaojing, Sun, Pingping, Lu, Shu, Liu, Chenxu, Zhu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027447/
https://www.ncbi.nlm.nih.gov/pubmed/35448958
http://dx.doi.org/10.1186/s12876-022-02260-7