Preclinical Pharmacokinetic Studies of a Novel Diuretic Inhibiting Urea Transporters

Urea transporter (UT) inhibitors are a class of promising novel diuretics that do not cause the imbalance of Na(+), K(+), Cl(−), and other electrolytes. In our previous studies, 25a, a promising diuretic candidate inhibiting UT, was discovered and showed potent diuretic activities in rodents. Here,...

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Detalles Bibliográficos
Autores principales: Xu, Yue, Zhang, Hang, Li, Nannan, Ma, Wen, Wang, Shuyuan, Sun, Jianguo, Yang, Baoxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027532/
https://www.ncbi.nlm.nih.gov/pubmed/35458649
http://dx.doi.org/10.3390/molecules27082451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027532/
https://www.ncbi.nlm.nih.gov/pubmed/35458649
http://dx.doi.org/10.3390/molecules27082451

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