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Preclinical Pharmacokinetic Studies of a Novel Diuretic Inhibiting Urea Transporters
Urea transporter (UT) inhibitors are a class of promising novel diuretics that do not cause the imbalance of Na(+), K(+), Cl(−), and other electrolytes. In our previous studies, 25a, a promising diuretic candidate inhibiting UT, was discovered and showed potent diuretic activities in rodents. Here,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027532/ https://www.ncbi.nlm.nih.gov/pubmed/35458649 http://dx.doi.org/10.3390/molecules27082451 |