Cargando…

Rituximab in Systemic Lupus Erythematosus: Transient Effects on Autoimmunity Associated Lymphocyte Phenotypes and Implications for Immunogenicity

B cell abnormalities are common in systemic lupus erythematosus (SLE), and include expansion of double negative (DN) and age-associated-like B cells (ABC-like). We aimed to investigate rituximab (RTX) effects on DN and ABC-like B-cell subsets and, when possible, also secondary effects on T cells. Fi...

Descripción completa

Detalles Bibliográficos
Autores principales: Faustini, Francesca, Sippl, Natalie, Stålesen, Ragnhild, Chemin, Karine, Dunn, Nicky, Fogdell-Hahn, Anna, Gunnarsson, Iva, Malmström, Vivianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027571/
https://www.ncbi.nlm.nih.gov/pubmed/35464461
http://dx.doi.org/10.3389/fimmu.2022.826152