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TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation

Women with autoimmune and inflammatory aetiologies can exhibit reduced fecundity. TNFAIP3 is a master negative regulator of inflammation, and has been linked to many inflammatory conditions by genome wide associations studies, however its role in fertility remains unknown. Here we show that mice har...

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Detalles Bibliográficos
Autores principales: Zammit, Nathan W., McDowell, Joseph, Warren, Joanna, Muskovic, Walter, Gamble, Joanne, Shi, Yan-Chuan, Kaczorowski, Dominik, Chan, Chia-Ling, Powell, Joseph, Ormandy, Chris, Brown, David, Oakes, Samantha R., Grey, Shane T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027572/
https://www.ncbi.nlm.nih.gov/pubmed/35464428
http://dx.doi.org/10.3389/fimmu.2022.811525