Dopamine Transporter, PhosphoSerine129 α-Synuclein and α-Synuclein Levels in Aged LRRK2 G2019S Knock-In and Knock-Out Mice

The G2019S mutation in leucine rich-repeat kinase 2 (LRRK2) is a major cause of familial Parkinson’s disease. We previously reported that G2019S knock-in mice manifest dopamine transporter dysfunction and phosphoSerine129 α-synuclein (pSer129 α-syn) immunoreactivity elevation at 12 months of age, wh...

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Detalles Bibliográficos
Autores principales: Domenicale, Chiara, Mercatelli, Daniela, Albanese, Federica, Novello, Salvatore, Vincenzi, Fabrizio, Varani, Katia, Morari, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027615/
https://www.ncbi.nlm.nih.gov/pubmed/35453631
http://dx.doi.org/10.3390/biomedicines10040881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027615/
https://www.ncbi.nlm.nih.gov/pubmed/35453631
http://dx.doi.org/10.3390/biomedicines10040881

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