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Sirtuin 3 Dependent and Independent Effects of NAD(+) to Suppress Vascular Inflammation and Improve Endothelial Function in Mice

Atherosclerosis is initiated by endothelial cell dysfunction and vascular inflammation under the condition of hyperlipidemia. Sirtuin 3 (SIRT3) is a nicotinamide adenine dinucleotide (NAD(+))-dependent mitochondrial deacetylase, which plays a key role in maintaining normal mitochondrial function. Th...

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Detalles Bibliográficos
Autores principales: Cao, Xiaoyun, Wu, Yalan, Hong, Huiling, Tian, Xiao Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027736/
https://www.ncbi.nlm.nih.gov/pubmed/35453391
http://dx.doi.org/10.3390/antiox11040706