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Sirtuin 3 Dependent and Independent Effects of NAD(+) to Suppress Vascular Inflammation and Improve Endothelial Function in Mice
Atherosclerosis is initiated by endothelial cell dysfunction and vascular inflammation under the condition of hyperlipidemia. Sirtuin 3 (SIRT3) is a nicotinamide adenine dinucleotide (NAD(+))-dependent mitochondrial deacetylase, which plays a key role in maintaining normal mitochondrial function. Th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027736/ https://www.ncbi.nlm.nih.gov/pubmed/35453391 http://dx.doi.org/10.3390/antiox11040706 |