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Therapeutic Targeting of Alternative Splicing: A New Frontier in Cancer Treatment

The ability for cells to harness alternative splicing enables them to diversify their proteome in order to carry out complex biological functions and adapt to external and internal stimuli. The spliceosome is the multiprotein-RNA complex charged with the intricate task of alternative splicing. Aberr...

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Detalles Bibliográficos
Autores principales: Murphy, Anthony J., Li, Alex H., Li, Peichao, Sun, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027816/
https://www.ncbi.nlm.nih.gov/pubmed/35463320
http://dx.doi.org/10.3389/fonc.2022.868664